BAY-1112054 hydrochloride
BAY-1112054 (BAY-958) hydrochloride is a potent PTEFb/CDK9 inhibitor with high selectivity demonstrated, particularly within the CDK family. BAY-1112054 hydrochloride shows strong antiproliferative activity against cancer cell lines such as HeLa and MOLM-13. BAY-1112054 hydrochloride exhibits good metabolic stability. BAY-1112054 hydrochloride effectively inhibits tumor growth in mouse xenograft models without significant toxicity.
For research use only. We do not sell to patients.
- CAS No.: 1424871-27-1
- Formula: C17H17ClFN5O3S
- Molecular Weight:425.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CDK9 |
Chemical Information
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CAS No. 1424871-27-1
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Molecular Weight 425.86
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Formula C17H17ClFN5O3S
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SMILES
O=S(CC1=CC=CC(NC2=NC(C3=CC=C(F)C=C3OC)=NC=N2)=C1)(N)=O.Cl
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Synonyms
BAY-958 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BAY-1112054 hydrochloride Related Classifications
HY-121081A Related Classifications
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