BAY-5000
Based on 1 Customer Validation
BAY-5000 (example 32) is a pyrimidinedione derivative. BAY-5000 can be used in the synthesis of cancer-related reagents.
For research use only. We do not sell to patients.
- Purity: 99.16%
- CAS No.: 2639435-48-4
- Formula: C22H14ClF3N2O3
- Molecular Weight:446.81
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
1 μM
Compound: 36
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Upregulation of BCAA expression in human MDA-MB-231 cells
Upregulation of BCAA expression in human MDA-MB-231 cells
|
[PMID: 36261130] |
| MDA-MB-231 | IC50 |
874 nM
Compound: 36a; BAY-069
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Upregulation of BCAA expression in human MDA-MB-231 cells
Upregulation of BCAA expression in human MDA-MB-231 cells
|
[PMID: 36261130] |
Chemical Information
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CAS No. 2639435-48-4
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Appearance Solid
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Molecular Weight 446.81
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Formula C22H14ClF3N2O3
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Color Off-white to light yellow
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SMILES
CC(C=CC=C1)=C1OC2=C(Cl)C3=C(C=CC=C3)C(N4C(NC(C(F)(F)F)=CC4=O)=O)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (559.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2381 mL | 11.1904 mL | 22.3809 mL | 55.9522 mL |
| 5 mM | 0.4476 mL | 2.2381 mL | 4.4762 mL | 11.1904 mL | |
| 10 mM | 0.2238 mL | 1.1190 mL | 2.2381 mL | 5.5952 mL | |
| 15 mM | 0.1492 mL | 0.7460 mL | 1.4921 mL | 3.7301 mL | |
| 20 mM | 0.1119 mL | 0.5595 mL | 1.1190 mL | 2.7976 mL | |
| 25 mM | 0.0895 mL | 0.4476 mL | 0.8952 mL | 2.2381 mL | |
| 30 mM | 0.0746 mL | 0.3730 mL | 0.7460 mL | 1.8651 mL | |
| 40 mM | 0.0560 mL | 0.2798 mL | 0.5595 mL | 1.3988 mL | |
| 50 mM | 0.0448 mL | 0.2238 mL | 0.4476 mL | 1.1190 mL | |
| 60 mM | 0.0373 mL | 0.1865 mL | 0.3730 mL | 0.9325 mL | |
| 80 mM | 0.0280 mL | 0.1399 mL | 0.2798 mL | 0.6994 mL | |
| 100 mM | 0.0224 mL | 0.1119 mL | 0.2238 mL | 0.5595 mL |
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