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United States

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Cat. No.: HY-155369

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BChE-IN-21

BChE-IN-21 is a potent BChE inhibitor with an IC₅₀ of 0.14 ± 0.02 μM. BChE-IN-21 has the potential for alzheimer's disease research.

For research use only. We do not sell to patients.

Formula: C₃₀H₂₅Br₂N₃O₂
Molecular Weight:619.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

BChE-IN-21 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

BChE-IN-21 is a potent BChE inhibitor with an IC₅₀ of 0.14 ± 0.02 μM. BChE-IN-21 has the potential for alzheimer's disease research^[1].

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Chemical Information

Molecular Weight 619.35
Formula C₃₀H₂₅Br₂N₃O₂
SMILES

O=C(NCC1=C[N+](CC2=CC=C(Br)C=C2)=CC=C1)C3=CC(C4=CC=C(OC)C=C4)=NC5=CC=CC=C53.[Br-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Milad Noori, et al. Phenyl-quinoline derivatives as a lead structure of cholinesterase inhibitor endowed with potency to reduce the GSK-3β level targeting Alzheimer's disease. Int J Biol Macromol. 2023 Oct 10:127392. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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BChE-IN-21

All Cholinesterase (ChE) Isoforms