BDM19
Based on 1 Customer Validation
BDM19 binds and activates cytosolic BAX dimers, and prompts cell apoptosis either alone or in combination with BCL-2/BCL-XL inhibitor Navitoclax (HY-10087).
For research use only. We do not sell to patients.
- Purity: 99.38%
- CAS No.: 500273-31-4
- Formula: C24H17IN2O3
- Molecular Weight:508.31
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
-
CAS No. 500273-31-4
-
Appearance Solid
-
Molecular Weight 508.31
-
Formula C24H17IN2O3
-
Color Off-white to light yellow
-
SMILES
CC1=CC(/C=C/C2=NC3=CC=C(I)C=C3C(N2C4=CC=C(C(O)=O)C=C4)=O)=CC=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (196.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9673 mL | 9.8365 mL | 19.6730 mL | 49.1826 mL |
| 5 mM | 0.3935 mL | 1.9673 mL | 3.9346 mL | 9.8365 mL | |
| 10 mM | 0.1967 mL | 0.9837 mL | 1.9673 mL | 4.9183 mL | |
| 15 mM | 0.1312 mL | 0.6558 mL | 1.3115 mL | 3.2788 mL | |
| 20 mM | 0.0984 mL | 0.4918 mL | 0.9837 mL | 2.4591 mL | |
| 25 mM | 0.0787 mL | 0.3935 mL | 0.7869 mL | 1.9673 mL | |
| 30 mM | 0.0656 mL | 0.3279 mL | 0.6558 mL | 1.6394 mL | |
| 40 mM | 0.0492 mL | 0.2459 mL | 0.4918 mL | 1.2296 mL | |
| 50 mM | 0.0393 mL | 0.1967 mL | 0.3935 mL | 0.9837 mL | |
| 60 mM | 0.0328 mL | 0.1639 mL | 0.3279 mL | 0.8197 mL | |
| 80 mM | 0.0246 mL | 0.1230 mL | 0.2459 mL | 0.6148 mL | |
| 100 mM | 0.0197 mL | 0.0984 mL | 0.1967 mL | 0.4918 mL |