BI-2865 (Standard)

BI-2865 (Standard) is the analytical standard of BI-2865 (HY-153724). This product is intended for research and analytical applications. BI-2865 is a none-covalent pan-KRAS Inhibitor. BI-2865 binds to WT, G12C, G12D, G12V and G13D mutant KRAS with KDs of 6.9, 4.5, 32, 26, 4.3 nM respectively. BI-2865 inhibits the proliferation of G12C, G12D or G12V mutant KRAS expressing BaF3 cells (mean IC50: roughly 140 nM).

For research use only. We do not sell to patients.

  • CAS No.: 2937327-93-8
  • Formula: C23H27N7O2S
  • Molecular Weight:465.57
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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