1. GPCR/G Protein
    Metabolic Enzyme/Protease
  2. Glucocorticoid Receptor
    HCV Protease
  3. BI 653048

BI 653048 

Cat. No.: HY-12946
Handling Instructions

BI 653048 is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with anti-inflammatory effects. BI 653048, compound 103 extracted from patent WO2005028501A1, is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus.

For research use only. We do not sell to patients.

BI 653048 Chemical Structure

BI 653048 Chemical Structure

CAS No. : 1198784-72-3

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Description

BI 653048 is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with anti-inflammatory effects[1]. BI 653048, compound 103 extracted from patent WO2005028501A1, is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus[2].

IC50 & Target

IC50: Glucocorticoid (GC)[1]

Molecular Weight

515.52

Formula

C₂₃H₂₅F₄N₃O₄S

CAS No.

1198784-72-3

SMILES

O=C(N)C1=CC(F)=CC=C1C(C)(C)C[[email protected]@](O)(CC(N2)=CC3=C2C=NC(S(=O)(CC)=O)=C3)C(F)(F)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

BI 653048BI653048BI-653048Glucocorticoid ReceptorHCV ProteaseHCVNS3proteaseInhibitorinhibitorinhibit

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BI 653048
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