Bis(N-methylthioformohydroxamate)nickel (II)
Bis(N-methylthioformohydroxamate)nickel (II) is an antibiotic containing metallic nickel with strong anti-Gram-positive and negative bacteria activity and anti-tumor activity.
For research use only. We do not sell to patients.
- CAS No.: 31541-90-9
- Formula: C4H8N2NiO2S2
- Molecular Weight:238.94
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Description
Chemical Information
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CAS No. 31541-90-9
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Molecular Weight 238.94
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Formula C4H8N2NiO2S2
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SMILES
CN(C=[S]1)[O-][Ni+2]21[S]=CN(C)[O-]2
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)