1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. BMS-191011

BMS-191011 (Synonyms: BMS-A)

Cat. No.: HY-108593 Purity: 98.93%
Handling Instructions

BMS-191011 (BMS-A) is an opener of the large-conductance, Ca2++-activated potassium (maxi-K) channel, effective in stroke models.

For research use only. We do not sell to patients.

BMS-191011 Chemical Structure

BMS-191011 Chemical Structure

CAS No. : 202821-81-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
5 mg USD 60 In-stock
Estimated Time of Arrival: December 31
10 mg USD 90 In-stock
Estimated Time of Arrival: December 31
50 mg USD 360 In-stock
Estimated Time of Arrival: December 31
100 mg USD 640 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

BMS-191011 (BMS-A) is an opener of the large-conductance, Ca2++-activated potassium (maxi-K) channel, effective in stroke models[1].

Molecular Weight

370.71

Formula

C₁₆H₁₀ClF₃N₂O₃

CAS No.

202821-81-6

SMILES

O=C1OC(C2=CC=C(C(F)(F)F)C=C2)=NN1CC3=CC(Cl)=CC=C3O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (337.19 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6975 mL 13.4876 mL 26.9753 mL
5 mM 0.5395 mL 2.6975 mL 5.3951 mL
10 mM 0.2698 mL 1.3488 mL 2.6975 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (5.61 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.61 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
BMS-191011
Cat. No.:
HY-108593
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