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Cat. No.: HY-117453
Handling Instructions

BMS-901715 is a potent and selective adapter protein-2 associated kinase 1 (AAK1) inhibitor with an IC50 of 3.3 nM.

For research use only. We do not sell to patients.

BMS-901715 Chemical Structure

BMS-901715 Chemical Structure

CAS No. : 1699861-37-4

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BMS-901715 is a potent and selective adapter protein-2 associated kinase 1 (AAK1) inhibitor with an IC50 of 3.3 nM[1][2].

IC50 & Target

IC50: 3.3 nM (Adapter protein-2 associated kinase 1 (AAK1))[2]

In Vitro

Adaptor associated kinase 1 (AAK1) is a member of the Ark1/Prk1 family of serine/threonine kinases. AAK1 mRNA exists in two splice forms termed short and long. The long form predominates and is highly expressed in brain and heart. AAK1 is enriched in synaptosomal preparations and is co-localized with endocytic structures in cultured cells. AAK1 modulates clatherin coated endocytosis, a process that is important in synaptic vesicle recycling and receptor-mediated endocytosis[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight





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