BMS-986020 (Standard)
BMS-986020 (Standard) is the analytical standard of BMS-986020 (HY-100619). This product is intended for research and analytical applications. BMS-986020 (AM152) is a high-affinity and selective lysophosphatidic acid receptor 1 (LPA1) antagonist. BMS-986020 inhibits bile acid and phospholipid transporters with IC50s of 4.8 μM, 6.2 μM, and 7.5 μM for BSEP, MRP4, and MDR3, respectively. BMS-986020 has the potential for the treatment of idiopathic pulmonary fibrosis (IPF).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98%
- No. CAS: 1257213-50-5
- Fòrmula: C29H26N2O5
- Peso molecular:482.53
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureza y Documentación
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Help & FAQs
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HY-100619
BMS-986020LPA1 Antagonist -
HY-13285
Ki16425LPA1/3 Antagonist -
HY-16040
AM095 free acid -
HY-139853
BMS-986278LPA1 Antagonist -
HY-16039
AM095LPA1 Antagonist -
HY-107614
1-Oleoyl lysophosphatidic acid sodiumLPA Receptor Activator -
HY-11063
FingolimodS1P Antagonist -
HY-15277
AM966LPA1 Receptor Antagonist -
HY-100882
ONO-7300243LPA1 Antagonist -
HY-18641
Ki16198LPA Receptor Antagonist -
HY-108496
Sphingosine-1-phosphateS1PR Agonist -
HY-101419
CYM-5541S1P3 Receptor Agonist
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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No. CAS 1257213-50-5
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Peso molecular 482.53
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Fòrmula C29H26N2O5
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SMILES
O=C(C1(C2=CC=C(C3=CC=C(C4=C(NC(O[C@@H](C5=CC=CC=C5)C)=O)C(C)=NO4)C=C3)C=C2)CC1)O
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Synonyms
AM152 (Standard)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Kihara Y, et al. Lysophospholipid receptors in drug discovery. Exp Cell Res. 2015 May 1;333(2):171-7. [Content Brief]
[3]. Palmer SM, et al. Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial of BMS-986020, a Lysophosphatidic Acid Receptor Antagonist for the Treatment of Idiopathic Pulmonary Fibrosis. Chest. 2018 Nov;154(5):1061-1069. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BMS-986020 (Standard) Related Classifications
HY-100619R Related Classifications
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