1. GPCR/G Protein
  2. LPL Receptor

BMS-986020 (Synonyms: AM152)

Cat. No.: HY-100619 Purity: 98.02%
Data Sheet SDS Handling Instructions

BMS-986020 is an LPA1 antagonist.

For research use only. We do not sell to patients.
BMS-986020 Chemical Structure

BMS-986020 Chemical Structure

CAS No. : 1257213-50-5

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 446 In-stock
1 mg USD 180 In-stock
5 mg USD 420 In-stock
10 mg USD 600 In-stock
50 mg USD 1800 In-stock
100 mg USD 2520 In-stock
200 mg   Get quote  
500 mg   Get quote  

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  • Biological Activity

  • Protocol

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  • References

Description

BMS-986020 is an LPA1 antagonist. target: LPA1 BMS-986020 is in Phase 2 clinical development for treating idiopathic pulmonary fibrosis. BMS-986020 selectively inhibits the LPA receptor, which is involved in binding of the signaling molecule lysophosphatidic acid, which in turn is involved in a host of diverse biological functions, such as cell proliferation, platelet aggregation, smooth muscle contraction and others.

Clinical Trial
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References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.0724 mL 10.3621 mL 20.7241 mL
5 mM 0.4145 mL 2.0724 mL 4.1448 mL
10 mM 0.2072 mL 1.0362 mL 2.0724 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

482.53

Formula

C₂₉H₂₆N₂O₅

CAS No.

1257213-50-5

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 64 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
BMS-986020
Cat. No.:
HY-100619
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