2. Others GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor Reference Standards 5-HT Receptor
  4. BMY 7378 (Standard)

BMY 7378 (Standard) is the analytical standard of BMY 7378 (HY-100554). This product is intended for research and analytical applications. BMY 7378 is a selective antagonist of α1D-adrenoceptor (α1D-AR). BMY 7378 binds to membranes expressing the cloned rat α1D-AR with a >100-fold higher affinity (Ki=2 nM) than binding to either the cloned rat α1A-AR (Ki=800 nM) or the hamster α1B-AR (Ki=600 nM). BMY 7378 is a 5-HT1A receptor partial agonist.

For research use only. We do not sell to patients.

BMY 7378 (Standard)

BMY 7378 (Standard) Chemical Structure

CAS No. : 21102-95-4

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Information

BMY 7378 (Standard) is the analytical standard of BMY 7378 (HY-100554). This product is intended for research and analytical applications. BMY 7378 is a selective antagonist of α1D-adrenoceptor (α1D-AR). BMY 7378 binds to membranes expressing the cloned rat α1D-AR with a >100-fold higher affinity (Ki=2 nM) than binding to either the cloned rat α1A-AR (Ki=800 nM) or the hamster α1B-AR (Ki=600 nM). BMY 7378 is a 5-HT1A receptor partial agonist.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

458.42

Formula

C22H33Cl2N3O3
CAS No.
SMILES

O=C(N(CCN1CCN(C2=CC=CC=C2OC)CC1)C(C3)=O)CC43CCCC4.[H]Cl.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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BMY 7378 (Standard) Related Classifications

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Keywords:

BMY 7378 (Standard)21102-95-4Adrenergic ReceptorReference Standards5-HT ReceptorBeta ReceptorSerotonin Receptor5-hydroxytryptamine Receptorselective5-HT1A receptoralpha 1-adrenoceptorspontaneously hypertensive ratsInhibitorinhibitorinhibit

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