Boc-GRR-AMC
Based on 1 Customer Validation
Boc-GRR-AMC is a tri-peptide Substrate. Boc-GRR-AMC can be used for a fluorogenic West Nile virus (WNV) substrate, profiling the substrate specificity for the NS2B-NS3 proteases or determining the pH optimum of LdMC activity.
For research use only. We do not sell to patients.
- Purity: 99.44%
- CAS No.: 113866-14-1
- Formula: C29H44N10O7
- Molecular Weight:644.72
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 113866-14-1
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Appearance Solid
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Molecular Weight 644.72
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Formula C29H44N10O7
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Color White to off-white
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Sequence
{Boc}-Gly-Arg-Arg-{AMC}
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Sequence Shortening
{Boc}-GRR-{AMC}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (155.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Nancy Lee, et al. Characterization of metacaspases with trypsin-like activity and their putative role in programmed cell death in the protozoan parasite Leishmania. Eukaryot Cell. 2007 Oct;6(10):1745-57. [Content Brief]
[2]. Manolya Ezgimen, et al.Characterization of the 8-hydroxyquinoline scaffold for inhibitors of West Nile virus serine protease. Antiviral Res. 2012 Apr;94(1):18-24. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5511 mL | 7.7553 mL | 15.5106 mL | 38.7765 mL |
| 5 mM | 0.3102 mL | 1.5511 mL | 3.1021 mL | 7.7553 mL | |
| 10 mM | 0.1551 mL | 0.7755 mL | 1.5511 mL | 3.8777 mL | |
| 15 mM | 0.1034 mL | 0.5170 mL | 1.0340 mL | 2.5851 mL | |
| 20 mM | 0.0776 mL | 0.3878 mL | 0.7755 mL | 1.9388 mL | |
| 25 mM | 0.0620 mL | 0.3102 mL | 0.6204 mL | 1.5511 mL | |
| 30 mM | 0.0517 mL | 0.2585 mL | 0.5170 mL | 1.2926 mL | |
| 40 mM | 0.0388 mL | 0.1939 mL | 0.3878 mL | 0.9694 mL | |
| 50 mM | 0.0310 mL | 0.1551 mL | 0.3102 mL | 0.7755 mL | |
| 60 mM | 0.0259 mL | 0.1293 mL | 0.2585 mL | 0.6463 mL | |
| 80 mM | 0.0194 mL | 0.0969 mL | 0.1939 mL | 0.4847 mL | |
| 100 mM | 0.0155 mL | 0.0776 mL | 0.1551 mL | 0.3878 mL |