Bortezomib impurity A

Cat. No.: HY-W048404 Purity: 99.75%: Data Sheet
COA

SDS
Handling Instructions
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Bortezomib impurity A is a metabolite of the 20S proteasome inhibitor Bortezomib (HY-10227).

For research use only. We do not sell to patients.

Bortezomib impurity A Chemical Structure

CAS No. : 289472-80-6

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Description

Bortezomib impurity A is a metabolite of the 20S proteasome inhibitor Bortezomib (HY-10227).

Molecular Weight

270.29

Formula

C₁₄H₁₄N₄O₂

CAS No.

289472-80-6

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=NC=CN=C1)N[C@@H](CC2=CC=CC=C2)C(N)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 10 mg/mL (37.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.6997 mL	18.4986 mL	36.9973 mL
5 mM	0.7399 mL	3.6997 mL	7.3995 mL
10 mM	0.3700 mL	1.8499 mL	3.6997 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.75%

Select Batch:

Data Sheet (245 KB) SDS (393 KB)

COA (251 KB) HNMR (252 KB) LCMS (104 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.6997 mL	18.4986 mL	36.9973 mL	92.4932 mL
	5 mM	0.7399 mL	3.6997 mL	7.3995 mL	18.4986 mL
	10 mM	0.3700 mL	1.8499 mL	3.6997 mL	9.2493 mL
	15 mM	0.2466 mL	1.2332 mL	2.4665 mL	6.1662 mL
	20 mM	0.1850 mL	0.9249 mL	1.8499 mL	4.6247 mL
	25 mM	0.1480 mL	0.7399 mL	1.4799 mL	3.6997 mL
	30 mM	0.1233 mL	0.6166 mL	1.2332 mL	3.0831 mL