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United States

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Cat. No.: HY-175909

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BTK ligand-18

BTK ligand-18 is a BTK ligand, which can be used for the synthesis of PROTACs, such as PROTAC BTK Degrader-9 (HY-162280).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₂₂H₂₄FN₉O
분자량:449.48

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

BTK ligand-18 Chemical Structure

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

BTK ligand-18 is a BTK ligand, which can be used for the synthesis of PROTACs, such as PROTAC BTK Degrader-9 (HY-162280)^[1].

Chemical Information

분자량 449.48
화학식 C₂₂H₂₄FN₉O
SMILES

CC1=CC(C2=NC(NC3=CNN=C3)=NC=C2F)=CC=C1CNC(C4=CN(C(C)(C)C)N=N4)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Huang J, et al. Discovery of Novel Potent and Fast BTK PROTACs for the Treatment of Osteoclasts-Related Inflammatory Diseases. J Med Chem. 2024 Feb 22;67(4):2438-2465. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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