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Art. -Nr.: HY-175909

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BTK ligand-18

BTK ligand-18 is a BTK ligand, which can be used for the synthesis of PROTACs, such as PROTAC BTK Degrader-9 (HY-162280).

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Formel: C₂₂H₂₄FN₉O
Molecular Weight:449.48

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

BTK ligand-18 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

BTK ligand-18 is a BTK ligand, which can be used for the synthesis of PROTACs, such as PROTAC BTK Degrader-9 (HY-162280)^[1].

Chemical Information

Molecular Weight 449.48
Formel C₂₂H₂₄FN₉O
SMILES

CC1=CC(C2=NC(NC3=CNN=C3)=NC=C2F)=CC=C1CNC(C4=CN(C(C)(C)C)N=N4)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Huang J, et al. Discovery of Novel Potent and Fast BTK PROTACs for the Treatment of Osteoclasts-Related Inflammatory Diseases. J Med Chem. 2024 Feb 22;67(4):2438-2465. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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