Butylboronic acid
Based on 1 Customer Validation
Butylboronic acid is a competitive soybean urease inhibitor with an IC50 of 2.9 mM and a Ki of 1.5 mM.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.21%
- CAS 番号: 4426-47-5
- 分子式: C4H11BO2
- 分子量:101.94
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
IC50: 2.9 mM (soybean (Glycine max) urease)[1]
Butylboronic acid (Ki = 1.50 mM, IC50 = 2.9 mM) exerts an inhibitory effect on soybean (Glycine max) urease through a competitive inhibition mechanism[1].
Butylboronic acid (0.1 mM; 3-28 days) promotes cell proliferation, alkaline phosphatase activity, and expression of GJA1, ALP, and NaBC1 in human dental pulp cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 4426-47-5
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性状 Solid
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分子量 101.94
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分子式 C4H11BO2
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Color White to off-white
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SMILES
CCCCB(O)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : ≥ 200 mg/mL (1961.94 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Sandeep Kumar, et al. Inhibition studies of soybean (Glycine max) urease with heavy metals, sodium salts of mineral acids, boric acid, and boronic acids. J Enzyme Inhib Med Chem. 2010 Oct;25(5):646-52. [Content Brief]
[2]. Nakano T, et al. Butylboronic acid promotes cell proliferation, alkaline phosphatase activity, and expression of GJA1, ALP, and NaBC1 in human dental pulp cells in vitro. Front Dent Med. 2025 Feb 11;6:1518389. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 9.8097 mL | 49.0485 mL | 98.0969 mL | 245.2423 mL |
| 5 mM | 1.9619 mL | 9.8097 mL | 19.6194 mL | 49.0485 mL | |
| 10 mM | 0.9810 mL | 4.9048 mL | 9.8097 mL | 24.5242 mL | |
| 15 mM | 0.6540 mL | 3.2699 mL | 6.5398 mL | 16.3495 mL | |
| 20 mM | 0.4905 mL | 2.4524 mL | 4.9048 mL | 12.2621 mL | |
| 25 mM | 0.3924 mL | 1.9619 mL | 3.9239 mL | 9.8097 mL | |
| 30 mM | 0.3270 mL | 1.6349 mL | 3.2699 mL | 8.1747 mL | |
| 40 mM | 0.2452 mL | 1.2262 mL | 2.4524 mL | 6.1311 mL | |
| 50 mM | 0.1962 mL | 0.9810 mL | 1.9619 mL | 4.9048 mL | |
| 60 mM | 0.1635 mL | 0.8175 mL | 1.6349 mL | 4.0874 mL | |
| 80 mM | 0.1226 mL | 0.6131 mL | 1.2262 mL | 3.0655 mL | |
| 100 mM | 0.0981 mL | 0.4905 mL | 0.9810 mL | 2.4524 mL |
Butylboronic acid 関連分類
HY-W000932 関連分類
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