Butyrolactone V
Butyrolactone V is a butanolide compound. Butyrolactone V shows antiplasmodial activity against Plasmodium falciparum K1 with an IC50 of 7.9 µg/ml.
For research use only. We do not sell to patients.
- CAS No.: 1151509-01-1
- Formula: C24H24O8
- Molecular Weight:440.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
IC50 & Target
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Plasmodium |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BEAS-2B | IC50 |
>20 μM
Compound: 8
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Antiproliferative activity against human BEAS2B cells after 24 hrs by CCK8 assay
Antiproliferative activity against human BEAS2B cells after 24 hrs by CCK8 assay
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[PMID: 30392953] |
| HCC1806 | IC50 |
>20 μM
Compound: 8
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Antiproliferative activity against human HCC1806 cells after 24 hrs by CCK8 assay
Antiproliferative activity against human HCC1806 cells after 24 hrs by CCK8 assay
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[PMID: 30392953] |
| HepG2 | IC50 |
>20 μM
Compound: 8
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Antiproliferative activity against human HepG2 cells after 24 hrs by CCK8 assay
Antiproliferative activity against human HepG2 cells after 24 hrs by CCK8 assay
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[PMID: 30392953] |
| HT-29 | IC50 |
>20 μM
Compound: 8
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Antiproliferative activity against human HT-29 cells after 24 hrs by CCK8 assay
Antiproliferative activity against human HT-29 cells after 24 hrs by CCK8 assay
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[PMID: 30392953] |
| PANC-1 | IC50 |
>20 μM
Compound: 8
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Antiproliferative activity against human PANC1 cells after 24 hrs by CCK8 assay
Antiproliferative activity against human PANC1 cells after 24 hrs by CCK8 assay
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[PMID: 30392953] |
Chemical Information
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CAS No. 1151509-01-1
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Molecular Weight 440.44
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Formula C24H24O8
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SMILES
O=C([C@](C(C1=CC=C(O)C=C1)=C2O)(CC3=CC=C4C(C[C@H](O)C(C)(C)O4)=C3)OC2=O)OC
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Structure Classification
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Initial Source
Aspergillus terreus BCC 4651
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Butyrolactone V Related Classifications
HY-N8383 Related Classifications
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