2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Butyryltimolol

Butyryltimolol, an effective precursor of Timolol, improves the corneal penetration of Timolol. Butyryltimolol is a β-adrenergic blocker.

For research use only. We do not sell to patients.

Butyryltimolol Chemical Structure

Butyryltimolol Chemical Structure

CAS No. : 106351-79-5

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Based on 1 publication(s) in Google Scholar

Other Forms of Butyryltimolol:

Butyryltimolol Related Antibodies

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Description

Butyryltimolol, an effective precursor of Timolol, improves the corneal penetration of Timolol[1]. Butyryltimolol is a β-adrenergic blocker[2].

IC50 & Target

β adrenergic receptor

 

In Vitro

Butyryltimolol, a prodrug of Timolol, is equally effective as 240-min nasolacrimal blockade in enhancing ocular drug absorption[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Butyryltimolol Related Antibodies
Molecular Weight

386.51

Formula

C17H30N4O4S
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CCCC(O[C@@H](CNC(C)(C)C)COC1=NSN=C1N2CCOCC2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (258.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5873 mL 12.9363 mL 25.8726 mL
5 mM 0.5175 mL 2.5873 mL 5.1745 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5873 mL 12.9363 mL 25.8726 mL 64.6814 mL
5 mM 0.5175 mL 2.5873 mL 5.1745 mL 12.9363 mL
10 mM 0.2587 mL 1.2936 mL 2.5873 mL 6.4681 mL
15 mM 0.1725 mL 0.8624 mL 1.7248 mL 4.3121 mL
20 mM 0.1294 mL 0.6468 mL 1.2936 mL 3.2341 mL
25 mM 0.1035 mL 0.5175 mL 1.0349 mL 2.5873 mL
30 mM 0.0862 mL 0.4312 mL 0.8624 mL 2.1560 mL
40 mM 0.0647 mL 0.3234 mL 0.6468 mL 1.6170 mL
50 mM 0.0517 mL 0.2587 mL 0.5175 mL 1.2936 mL
60 mM 0.0431 mL 0.2156 mL 0.4312 mL 1.0780 mL
80 mM 0.0323 mL 0.1617 mL 0.3234 mL 0.8085 mL
100 mM 0.0259 mL 0.1294 mL 0.2587 mL 0.6468 mL
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Butyryltimolol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Butyryltimolol106351-79-5Adrenergic ReceptorBeta ReceptorprodrugTimololcornealpenetrationβ-adrenergicblockerabsorptionInhibitorinhibitorinhibit

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