C-176 (Standard)
C-176 (Standard) is the analytical standard of C-176 (HY-112906). This product is intended for research and analytical applications. C-176 is a selective and blood-brain barrier permeable STING inhibitor. C-176 covalently targets transmembrane cysteine residue 91 and thereby blocKing activation-induced palmitoylation of STING.
For research use only. We do not sell to patients.
- CAS No.: 314054-00-7
- Formula: C11H7IN2O4
- Molecular Weight:358.09
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 314054-00-7
-
Molecular Weight 358.09
-
Formula C11H7IN2O4
-
SMILES
O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(I)C=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Haag SM, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559(7713):269-273. [Content Brief]
[2]. Zhang LM, et al. STING mediates neuroinflammatory response by activating NLRP3-related pyroptosis in severe traumatic brain injury. J Neurochem. 2022 Sep;162(5):444-462. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
C-176 (Standard) Related Classifications
HY-112906R Related Classifications
Powered by Bioz