C-176 (Standard)
C-176 (Standard) is the analytical standard of C-176 (HY-112906). This product is intended for research and analytical applications. C-176 is a selective and blood-brain barrier permeable STING inhibitor. C-176 covalently targets transmembrane cysteine residue 91 and thereby blocKing activation-induced palmitoylation of STING.
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- No. CAS: 314054-00-7
- Fòrmula: C11H7IN2O4
- Peso molecular:358.09
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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No. CAS 314054-00-7
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Peso molecular 358.09
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Fòrmula C11H7IN2O4
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SMILES
O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(I)C=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Haag SM, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559(7713):269-273. [Content Brief]
[2]. Zhang LM, et al. STING mediates neuroinflammatory response by activating NLRP3-related pyroptosis in severe traumatic brain injury. J Neurochem. 2022 Sep;162(5):444-462. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)