1. Protein Tyrosine Kinase/RTK
  2. c-Kit
  3. c-Kit-IN-2

c-Kit-IN-2 

Cat. No.: HY-128602
Handling Instructions

c-Kit-IN-2 is a c-KIT inhibitor with an IC50 of 82 nM, shows superior antiproliferative activities against all the three GIST cell lines, GIST882, GIST430, and GIST48, with GI50s of 3, 1, and 2 nM, respectively.

For research use only. We do not sell to patients.

c-Kit-IN-2 Chemical Structure

c-Kit-IN-2 Chemical Structure

CAS No. : 2121515-37-3

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Description

c-Kit-IN-2 is a c-KIT inhibitor with an IC50 of 82 nM, shows superior antiproliferative activities against all the three GIST cell lines, GIST882, GIST430, and GIST48, with GI50s of 3, 1, and 2 nM, respectively[1].

IC50 & Target

IC50: 82 nM (c-KIT)[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

519.62

Formula

C₂₅H₂₉N₉O₂S

CAS No.

2121515-37-3

SMILES

CCN1CCN(C2=CC(NC3=NC=C(C4=CC=C(NC(NC5=NOC(CC)=C5)=O)C=C4)S3)=NC=N2)CC1

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
c-Kit-IN-2
Cat. No.:
HY-128602
Quantity:

c-Kit-IN-2

Cat. No.: HY-128602