24(R)-Hydroxycholesterol
Based on 1 Customer Validation
24(R)-Hydroxycholesterol (24R-OHC) is a key intermediate of Tacalcitol (HY-32337).
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 27460-26-0
- Formula: C27H46O2
- Molecular Weight:402.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-16940
24(S)-Hydroxycholesterol
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HY-16972
SR9243
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HY-10627
GW3965
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HY-10627A
GW3965 hydrochloride
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HY-N2371
27-Hydroxycholesterol
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HY-125772
Acetyl podocarpic acid anhydride
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HY-10629
LXR-623
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HY-101442
SR9238
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HY-137307
Cholest-5-ene-3ß,22(S)-diol
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HY-N1459
Campesterol
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HY-108688
GSK2033
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HY-116969
22(R)-Hydroxycholesterol
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
37 nM
Compound: 33
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Positive allosteric modulation of recombinant human GluN1/GluN2A receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamate-induced channel current at -70 mV holding potential by IonWork two-electrode voltage clamp method
Positive allosteric modulation of recombinant human GluN1/GluN2A receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamate-induced channel current at -70 mV holding potential by IonWork two-electrode voltage clamp method
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[PMID: 31390523] |
| HEK293 | EC50 |
55 nM
Compound: 33
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Positive allosteric modulation of recombinant human GluN1/GluN2B receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamate-induced channel current at -70 mV holding potential by IonWork two-electrode voltage clamp method
Positive allosteric modulation of recombinant human GluN1/GluN2B receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamate-induced channel current at -70 mV holding potential by IonWork two-electrode voltage clamp method
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[PMID: 31390523] |
Chemical Information
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CAS No. 27460-26-0
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Appearance Solid
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Molecular Weight 402.65
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Formula C27H46O2
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Color White to off-white
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SMILES
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CC[C@@H](O)C(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C
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Synonyms
24R-OHC; 24R-HC; 24(R)-Cerebrosterol
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
Chloroform : 5 mg/mL (12.42 mM; Need ultrasonic)
Ethanol : 2.5 mg/mL (6.21 mM; ultrasonic and warming and heat to 60°C)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / Chloroform | 1 mM | 2.4835 mL | 12.4177 mL | 24.8355 mL | 62.0887 mL |
| 5 mM | 0.4967 mL | 2.4835 mL | 4.9671 mL | 12.4177 mL | |
| Chloroform | 10 mM | 0.2484 mL | 1.2418 mL | 2.4835 mL | 6.2089 mL |
24(R)-Hydroxycholesterol Related Classifications
HY-16940A Related Classifications
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