ABT-751 (Standard)
ABT-751 (Standard) is the analytical standard of ABT-751. This product is intended for research and analytical applications. ABT-751 (E7010) is a novel, highly orally bioavailable sulfonamides antimitotic compound and tubulin binder. It prevents tubulin aggregation by binding to the colchicine site on β-tubulin, leading to cell cycle arrest in G2/M phase and inducing apoptosis, thus effectively preventing cell division. ABT-751 induces autophagy by inhibiting the AKT/MTOR signaling pathway. ABT-751 showed significant inhibition against various types of cancer cells, including lung, gastric, colon, and breast cancer.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 141430-65-1
- Formula: C18H17N3O4S
- Molecular Weight:371.41
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
-
HY-13270
ABT-751Sulfonamides Antimitotic Compounds/Tubulin Binders Agent -
HY-13520
NocodazoleMicrotubule Inhibitor -
HY-B0015
PaclitaxelAntitumor Agent -
HY-16569
ColchicineTubulin Inhibitor -
HY-15459
Cabazitaxel -
HY-B0011
DocetaxelTubulin Stabilizer -
HY-12053A
Vinorelbine ditartrateAnti-mitotic Agent -
HY-B0015R
Paclitaxel (Standard)Antitumor Agent -
HY-N0488
Vincristine sulfateAntineoplastic Agent -
HY-16569R
Colchicine (Standard)Tubulin Inhibitor -
HY-13520R
Nocodazole (Standard)Microtubule Inhibitor -
HY-16565
10-Deacetylbaccatin IIIIntermediate
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 141430-65-1
-
Molecular Weight 371.41
-
Formula C18H17N3O4S
-
SMILES
COC1=CC=C(C=C1)S(=O)(NC2=C(N=CC=C2)NC3=CC=C(C=C3)O)=O
-
Synonyms
E7010 (Standard)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ABT-751 (Standard) Related Classifications
HY-13270R Related Classifications
Powered by Bioz