DBCO-Cy3
Based on 2 publication(s) in Google Scholar
DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dyewith excitation maximum 555 nm and emission maximum of 580nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations. DBCO-Cy3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Purity: 93.92%
- CAS No.: 1782950-79-1
- Formula: C50H54N4O11S3
- Molecular Weight:983.18
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications Citing Use of MedChemExpress (MCE) DBCO-Cy3
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Biological Activity
Orange fluorescent dye
DBCO-Cy3 exhibits less background than TAMRA and most other commonly used fluorescent dyes.DBCO-Cy3 can be conjugated to antibodies, peptides, and proteins, it can be excited using the 532 nm or 555 nm laser line and visualized with TRITC filter sets.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
570
550
Chemical Information
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CAS No. 1782950-79-1
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Appearance Solid
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Molecular Weight 983.18
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Formula C50H54N4O11S3
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Color Purple to purplish red
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SMILES
O=S(CCC[N+]1=C(/C=C/C=C2N(CCCCCC(NCCC(N3C4=CC=CC=C4C#CC5=CC=CC=C5C3)=O)=O)C6=C(C=C(S(=O)(O)=O)C=C6)C/2(C)C)C(C)(C)C7=C1C=CC(S(=O)(O)=O)=C7)([O-])=O
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Synonyms
DBCO-Sulfo-Cy3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (2)
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Journal Impact Factor
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Most Recent
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Biosens Bioelectron
Electrochemically activated DNA circuit for the amplified and accurate biosensing of cancer cells. [Abstract]2026 Nov 1:311:118907. PMID: 42259088 -
Solvent & Solubility
DMSO : 125 mg/mL (127.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (251 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0171 mL | 5.0855 mL | 10.1711 mL | 25.4277 mL |
| 5 mM | 0.2034 mL | 1.0171 mL | 2.0342 mL | 5.0855 mL | |
| 10 mM | 0.1017 mL | 0.5086 mL | 1.0171 mL | 2.5428 mL | |
| 15 mM | 0.0678 mL | 0.3390 mL | 0.6781 mL | 1.6952 mL | |
| 20 mM | 0.0509 mL | 0.2543 mL | 0.5086 mL | 1.2714 mL | |
| 25 mM | 0.0407 mL | 0.2034 mL | 0.4068 mL | 1.0171 mL | |
| 30 mM | 0.0339 mL | 0.1695 mL | 0.3390 mL | 0.8476 mL | |
| 40 mM | 0.0254 mL | 0.1271 mL | 0.2543 mL | 0.6357 mL | |
| 50 mM | 0.0203 mL | 0.1017 mL | 0.2034 mL | 0.5086 mL | |
| 60 mM | 0.0170 mL | 0.0848 mL | 0.1695 mL | 0.4238 mL | |
| 80 mM | 0.0127 mL | 0.0636 mL | 0.1271 mL | 0.3178 mL | |
| 100 mM | 0.0102 mL | 0.0509 mL | 0.1017 mL | 0.2543 mL |