Jun11165
Jun11165 is a SARS-CoV-2 PLpro inhibitor (IC50 ≤ 0.6 μM), which inhibits SARS-CoV-2 with an EC50 value of ≤ 6 μM. Jun11165 can be used in the research of viral infections.
For research use only. We do not sell to patients.
- Formula: C22H24N2O2S
- Molecular Weight:380.50
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: ≤ 0.6 μM (SARS-CoV-2 PLpro)[1]
EC50: ≤ 6 μM (SARS-CoV-2)[1].
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Vero C1008 | CC50 |
>30 μM
Compound: Jun11165
|
Cytotoxicity against African green monkey Vero E6 cells incubated for 48 hrs by neutral red uptake assay
Cytotoxicity against African green monkey Vero E6 cells incubated for 48 hrs by neutral red uptake assay
|
[PMID: 38065031] |
Chemical Information
-
Molecular Weight 380.50
-
Formula C22H24N2O2S
-
SMILES
C[C@@H](NC(C1=CC(OCCN)=CC=C1C)=O)C2=CC(C3=CSC=C3)=CC=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)