Laventatug
Based on 1 Customer Validation
Laventatug (BRY-812 Antibody) is a humanized IgG1-kappa monoclonal antibody targeting hSLC39A6. Laventatug serves as the antibody component for the synthesis of the ADC molecule BRY-812 and exhibits anti-tumor activity.
For research use only. We do not sell to patients.
- Purity : 95.534%
- CAS No.: 3009829-91-5
- Molecular Weight:146.818 kDa
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Storage:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
[1]|
SLC39A6/ZIP6 |
In Vitro
BRY812 is an ADC targeting SLC39A6 that significantly inhibits the growth, stemness, and metastasis of colorectal cancer cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-kappa
Application
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized LIV-1/SLC39A6 Protein, Human (HEK293, His, HY-P78749) can bind Laventatug. The EC50 for this effect is 11.09 ng/mL.
Chemical Information
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CAS No. 3009829-91-5
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Appearance Liquid
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Molecular Weight 146.818 kDa
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Color Colorless to light yellow
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SMILES
N/A
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Synonyms
BRY-812 Antibody
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)