S-312
S-312 is a calcium antagonist with a bicyclic dihydrothienopyridine structure. S-312 can relax the helical strips of various isolated rabbit arteries procontracted with high potassium depolarizaiton. S-312 competitively imhibits calcium-induced contractions in depolarized basilar and femoral arteries. S-312 increases AV nodal conduction time in Langenedorff-perfused isolated rabbit hearts. S-312 exhibits vasculoselectivity, particularly for cerebral vessel.
For research use only. We do not sell to patients.
- CAS No.: 120004-07-1
- Formula: C20H22N2O4S
- Molecular Weight:386.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Calcium Channel Isoforms
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Biological Activity
Chemical Information
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CAS No. 120004-07-1
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Molecular Weight 386.46
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Formula C20H22N2O4S
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SMILES
O=C(C1=C(C)NC2=C(C1C3=CC([N+]([O-])=O)=CC=C3)C(CC(C)C)=CS2)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)