(S)-Tersolisib
Based on 1 Customer Validation
(S)-STX-478 is the S-enantiomer of STX-478. STX-478 is a selective inhibitor of PI3Kα mutants, preventing metabolic dysfunction and demonstrating antitumor activity in xenograft mouse models with PI3Kα mutant tumors.
For research use only. We do not sell to patients.
- Purity: 99.18%
- CAS No.: 2883540-91-6
- Formula: C16H12F5N5O2
- Molecular Weight:401.29
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 2883540-91-6
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Appearance Solid
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Molecular Weight 401.29
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Formula C16H12F5N5O2
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Color White to off-white
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SMILES
NC1=NC=C(C=N1)NC(N[C@@H](C2=C(C3=CC(F)=CC(F)=C3O2)C)C(F)(F)F)=O
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Synonyms
(S)-STX-478; (S)-STX-478-101; (S)-LY4064809
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (249.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4920 mL | 12.4598 mL | 24.9196 mL | 62.2991 mL |
| 5 mM | 0.4984 mL | 2.4920 mL | 4.9839 mL | 12.4598 mL | |
| 10 mM | 0.2492 mL | 1.2460 mL | 2.4920 mL | 6.2299 mL | |
| 15 mM | 0.1661 mL | 0.8307 mL | 1.6613 mL | 4.1533 mL | |
| 20 mM | 0.1246 mL | 0.6230 mL | 1.2460 mL | 3.1150 mL | |
| 25 mM | 0.0997 mL | 0.4984 mL | 0.9968 mL | 2.4920 mL | |
| 30 mM | 0.0831 mL | 0.4153 mL | 0.8307 mL | 2.0766 mL | |
| 40 mM | 0.0623 mL | 0.3115 mL | 0.6230 mL | 1.5575 mL | |
| 50 mM | 0.0498 mL | 0.2492 mL | 0.4984 mL | 1.2460 mL | |
| 60 mM | 0.0415 mL | 0.2077 mL | 0.4153 mL | 1.0383 mL | |
| 80 mM | 0.0311 mL | 0.1557 mL | 0.3115 mL | 0.7787 mL | |
| 100 mM | 0.0249 mL | 0.1246 mL | 0.2492 mL | 0.6230 mL |
(S)-Tersolisib Related Classifications
HY-156681A Related Classifications
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