27-Hydroxycholesterol (Standard)
27-Hydroxycholesterol (27-OHC) is a selective estrogen receptor modulator and an agonist of the liver X receptor.
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- CAS No.: 20380-11-4
- Formule: C27H46O2
- Masse moléculaire:402.65
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-N2371
27-HydroxycholesterolLXR Agonist -
HY-10627A
GW3965 hydrochlorideLXR Agonist -
HY-N1459
CampesterolEndogenous Metabolite -
HY-16940
24(S)-HydroxycholesterolEndogenous Metabolite -
HY-113134
25-HydroxycholesterolCholesterol Metabolite -
HY-116969
22(R)-HydroxycholesterolEndogenous Metabolite -
HY-N0835
(20S)-ProtopanaxatriolLXRα Inhibitor -
HY-B0141
EstradiolHuman Endogenous Metabolite -
HY-18282
AZ876LXR Agonist -
HY-16972
SR9243LXR Inverse Agonist -
HY-N1459R
Campesterol (Standard)Endogenous Metabolite -
HY-10627
GW3965LXR Agonist
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 20380-11-4
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Masse moléculaire 402.65
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Formule C27H46O2
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SMILES
C[C@@H](CO)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
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Synonyms
27-OHC (Standard)
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Structure Classification
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. DuSell CD, et al. 27-hydroxycholesterol is an endogenous selective estrogen receptor modulator. Mol Endocrinol. 2008 Jan;22(1):65-77. [Content Brief]
[2]. Raza S, et al. The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells. Cancer Cell Int. 2017 May 11;17:52. [Content Brief]
[3]. Kimbung S, et al. Impact of 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol in breast cancer. Endocr Relat Cancer. 2017 Jul;24(7):339-349. [Content Brief]
[4]. Fu X, et al. 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells. J Biol Chem. 2001 Oct 19;276(42):38378-87. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
27-Hydroxycholesterol (Standard) Related Classifications
HY-N2371R Related Classifications
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