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Cat. No.: HY-136345A

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3'-Hydroxy simvastatin

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3'-Hydroxy simvastatin is a metabolite of simvastatin. Simvastatin (HY-17502) is an orally active competitive inhibitor of HMG-CoA reductase (HMGCR) (K_i: 0.2 nM).

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Pureté: 99.71%
CAS No.: 1283861-33-5
Formule: C₂₅H₃₈O₆
Masse moléculaire:434.57

Stockage:

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

3'-Hydroxy simvastatin Chemical Structure

CAS No.: 1283861-33-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

3'-Hydroxy simvastatin is a metabolite of simvastatin. Simvastatin (HY-17502) is an orally active competitive inhibitor of HMG-CoA reductase (HMGCR) (K_i: 0.2 nM)^[1].

Chemical Information

CAS No. 1283861-33-5
Appearance Solid
Masse moléculaire 434.57
Formule C₂₅H₃₈O₆
Color White to off-white
SMILES

[H][C@@]1([C@H](C=CC2=C[C@@H](C[C@@H]([C@@]21[H])OC(C(C)(C(O)C)C)=O)C)C)CC[C@@]3([H])OC(C[C@@H](C3)O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Slater EE, et al. Mechanism of action and biological profile of HMG CoA reductase inhibitors. A new therapeutic alternative. Drugs. 1988;36 Suppl 3:72-82. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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