Acamelin
Acamelin is a Benzofuranoquinone compound that acts as a contact sensitizer. It can be isolated from the heartwood of Acacia melanoxylon R. Br., an Australian blackwood. Acamelin induces positive skin reactions and contact allergy in guinea pigs. It is applicable to research related to allergic contact dermatitis.
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- CAS No.: 74161-27-6
- Formule: C10H8O4
- Masse moléculaire:192.17
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Activité biologique
Description
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Pirbright white-strain (female, allergic contact dermatitis model)[1]
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Dosage:1% concentration
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Administration:epicutaneous; single application
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Result:Elicited ++ skin reaction in 2 of 5 guinea pigs, + reaction in 2, and (+) reaction in 1 at 24 hours post-challenge.
Elicited ++ skin reaction in 2 of 5 guinea pigs, + reaction in 2, and (+) reaction in 1 at 48 hours post-challenge.
Induced slightly stronger and longer-lasting skin reactions than co-isolated 2,6-dimethoxy-1,4-benzoquinone.
Chemical Information
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CAS No. 74161-27-6
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Appearance Solid
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Masse moléculaire 192.17
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Formule C10H8O4
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Color Orange to red
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SMILES
O=C(C=C(C1=O)OC)C2=C1OC(C)=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Acamelin Related Classifications
HY-119958 Related Classifications
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