Antibacterial agent 229
Antibacterial agent 229 (compound 8a) is a potent antibacterial agent. Antibacterial agent 229 shows antibacterial and antifungal abilities. Antibacterial agent 229 disrupts the integrity of the bacterial membrane, intercalates into DNA. Antibacterial agent 229 inhibits topoisomerase IV with an IC50 value of 10.88 µM.
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- CAS No.: 3049500-54-8
- Formule: C16H14ClFN6OS2
- Masse moléculaire:424.90
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Description
IC50 & Target
[1]|
TOPO IV 10.88 μM (IC50) |
In Vitro
Antibacterial agent 229 (compound 8a) shows antibacterial and antifungal abilities with MIC Values of 0.0377, 0.0047, 0.0189, 0.0189, 0.0189, 0.0189, 0.0047 mM for S. aureus ATCC 25923, S. aureus ATCC 29213, E. coli ATCC 25922, P. aeruginosa ATCC 27853, C. albicans ATCC 9002, C. albicans, C. parapsilosis ATCC 22019, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3049500-54-8
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Masse moléculaire 424.90
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Formule C16H14ClFN6OS2
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SMILES
O=C1C(C2=CSC(N)=N2)=CN(C/C(C)=N/NC(N)=S)C3=CC(Cl)=C(F)C=C31
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antibacterial agent 229 Related Classifications
HY-161813 Related Classifications
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