Azido-PEG1
Based on 1 Customer Validation
Azido-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- Pureté: 99.98%
- CAS No.: 1517-05-1
- Formule: C2H5N3O
- Masse moléculaire:87.08
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Stockage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Voir tous les produits spécifiques à Isoform PROTAC Linkers
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Activité biologique
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1517-05-1
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Appearance Liquid (Density: 1.146 g/cm3)
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Masse moléculaire 87.08
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Formule C2H5N3O
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Color Colorless to light yellow
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SMILES
[N-]=[N+]=NCCO
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
DMSO : ≥ 100 mg/mL (1148.37 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 11.4837 mL | 57.4185 mL | 114.8369 mL | 287.0923 mL |
| 5 mM | 2.2967 mL | 11.4837 mL | 22.9674 mL | 57.4185 mL | |
| 10 mM | 1.1484 mL | 5.7418 mL | 11.4837 mL | 28.7092 mL | |
| 15 mM | 0.7656 mL | 3.8279 mL | 7.6558 mL | 19.1395 mL | |
| 20 mM | 0.5742 mL | 2.8709 mL | 5.7418 mL | 14.3546 mL | |
| 25 mM | 0.4593 mL | 2.2967 mL | 4.5935 mL | 11.4837 mL | |
| 30 mM | 0.3828 mL | 1.9139 mL | 3.8279 mL | 9.5697 mL | |
| 40 mM | 0.2871 mL | 1.4355 mL | 2.8709 mL | 7.1773 mL | |
| 50 mM | 0.2297 mL | 1.1484 mL | 2.2967 mL | 5.7418 mL | |
| 60 mM | 0.1914 mL | 0.9570 mL | 1.9139 mL | 4.7849 mL | |
| 80 mM | 0.1435 mL | 0.7177 mL | 1.4355 mL | 3.5887 mL | |
| 100 mM | 0.1148 mL | 0.5742 mL | 1.1484 mL | 2.8709 mL |
Azido-PEG1 Related Classifications
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