Balhimycin
Balhimycin is a glycopeptide antibiotic, found from the fermentation broth of a Amycolatopsis sp. Balhimycin shows anti-bacterial activity against staphylococci and anaerobes.
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- CAS No.: 140932-79-2
- Formule: C66H73Cl2N9O24
- Masse moléculaire:1447.24
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
IC50 & Target
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Glycopeptide |
In Vitro
Balhimycin (0.39-12.5 μg/mL; 18 h) shows bactericidal activity against S. aureus, Streptococcus epidermidis, and streptococcal strains[1].
Balhimycin (0.39-12.5 μg/mL; 18 h) shows good bactericidal activity against different Staphylococcal strains[1].
Balhimycin (1-15 μg/mL; 30 min) leads to cell membrane scrambling of platelets, and shows stimulation of platelet apoptosis[2]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Staphylococcus aureus 209P, S. aureus 3066, S. aureus 20424, S. epidermidis 178, S. epidermidis 825, S. epidermidis 823, S. haemolyticus 712, S. haemolyticus 809, Streptococcus ATCC 29212, S. faecalis D 21777, S. faecalis D Endococcen, S. faecium D-59, S. faecium D-65
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Concentration:0.39-12.5 μg/mL
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Incubation Time:18 hours
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Result:Showed MIC values ranging from 0.39 μg/mL to 12.5 μg/mL against S. aureus, Streptococcus epidermidis, and streptococcal strains.
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Cell Line:Staphylococcus aureus 3066, S. aureus 20424, S. epidermidis 825, S. haemolyticus 712, Streptococcus faecalis ATCC29212, S. faecalis D 21777, S. faecalis D-59
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Concentration:0.39-1.56 μg/mL
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Incubation Time:18 hours
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Result:Showed MIC values ranging from 0.39 μg/mL to 1.56 μg/mL against staphylococcal strains.
Chemical Information
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CAS No. 140932-79-2
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Masse moléculaire 1447.24
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Formule C66H73Cl2N9O24
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Nadkarni SR, et al. Balhimycin, a new glycopeptide antibiotic produced by Amycolatopsis sp. Y-86,21022. Taxonomy, production, isolation and biological activity. J Antibiot (Tokyo). 1994 Mar;47(3):334-41. [Content Brief]
[2]. Towhid ST, et al. Stimulation of platelet apoptosis by balhimycin. Biochem Biophys Res Commun. 2013 May 31;435(2):323-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Balhimycin Related Classifications
HY-148209 Related Classifications
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