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Cat. No.: HY-143465

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BChE-IN-5

BChE-IN-5 is a potent and selective BChE inhibitor of hBChE over hAChE with an IC₅₀ of 2.8 nM for BChE. BChE-IN-5 has the potential for the research of alzheimer’s disease.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 2983586-25-8
Formule: C₃₀H₄₂N₄O
Masse moléculaire:474.68

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

BChE-IN-5 Chemical Structure

CAS No.: 2983586-25-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

BChE-IN-5 is a potent and selective BChE inhibitor of hBChE over hAChE with an IC₅₀ of 2.8 nM for BChE. BChE-IN-5 has the potential for the research of alzheimer’s disease^[1].

IC₅₀ & Target

AChE

BChE

Voir tous les produits spécifiques à Isoform Cholinesterase (ChE) :

AChE
BChE

In Vitro

BChE-IN-5 (compound 18) shows inhibitory potencies for hBChE and hAChE with IC₅₀s of 2.8 nM, 16000 nM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2983586-25-8
Masse moléculaire 474.68
Formule C₃₀H₄₂N₄O
SMILES

O=C(NCCC1CCN(CCC1)CC2=CC=CC=C2)[C@@H](NCCCC)CC3=CNC4=CC=CC=C34
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Meden A, et al. Structure-activity relationship study of tryptophan-based butyrylcholinesterase inhibitors. Eur J Med Chem. 2020 Dec 15;208:112766. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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BChE-IN-5

Voir tous les produits spécifiques à Isoform Cholinesterase (ChE)