BF 227 (Standard)
BF 227 (Standard) is the analytical standard of BF 227 (HY-105252A). This product is intended for research and analytical applications. BF 227 is a candidate for an amyloid imaging probe for PET, with a Ki of 4.3 nM for Aβ1-42 fibrils.
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- CAS No.: 845647-80-5
- Formule: C16H16FN3O2S
- Masse moléculaire:333.38
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 845647-80-5
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Masse moléculaire 333.38
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Formule C16H16FN3O2S
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SMILES
CN(C)C1=NC=C(S1)/C=C/C2=NC3=CC=C(OCCF)C=C3O2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Kudo Y, et al. Development of amyloid imaging PET probes for an early diagnosis of Alzheimer's disease. Minim Invasive Ther Allied Technol. 2006;15(4):209-13. [Content Brief]
[2]. Furukawa K, et al. Amyloid PET in mild cognitive impairment and Alzheimer's disease with BF-227: comparison to FDG-PET. J Neurol. 2010 May;257(5):721-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)