BRD-8899
BRD-8899 is a STK33 inhibitor, with an IC50 of 11 nM.
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- CAS No.: 1404437-50-8
- Formule: C17H22N4O3S
- Masse moléculaire:362.45
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
IC50: 11 nM (STK33)[1].
In Vitro
BRD8899 (1, 10, 20 μM, 24 h) results in decreased phosphorylation of the MST4 substrate ezrin in NOMO-1 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
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Cell Line:NOMO-1 cells.
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Concentration:1, 10, 20 μM.
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Incubation Time:24 h.
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Result:Decreased p-Ezrin levels.
Chemical Information
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CAS No. 1404437-50-8
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Masse moléculaire 362.45
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Formule C17H22N4O3S
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SMILES
CC1=C2C(C=CC=C2S(N[C@@H]3C[C@@H](CNC(C)=O)NC3)(=O)=O)=CN=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRD-8899 Related Classifications
HY-13498 Related Classifications
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