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Cat. No.: HY-181436

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CAY10563

CAY10563 is a pH-regulated NO donor. Under acidic conditions, CAY10563 releases NO via an acid-catalyzed ring-opening mechanism, generating sulfur-centered free radicals. CAY10563 induces pH-dependent vasodilation. CAY10563 can be used in studies related to cardiovascular and cerebrovascular diseases.

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CAS No.: 940952-42-1
Formule: C₉H₄F₃NO₂S
Masse moléculaire:247.19

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Please store the product under the recommended conditions in the Certificate of Analysis.

CAY10563 Chemical Structure

CAS No.: 940952-42-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
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Description

Voir tous les produits spécifiques à Isoform NO Synthase :

In Vitro

CAY10563 (Compound 3a) (20 mM) releases NO in an acid-dependent manner at pH 5.0, with an overall NO yield of approximately 27%. No NO release is detected under neutral pH conditions, and it induces the formation of sulfur-centered radicals^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 940952-42-1
Masse moléculaire 247.19
Formule C₉H₄F₃NO₂S
SMILES

[O-]C1=C(C2=CC=C(C=C2)C(F)(F)F)[S+]=NO1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Lu D, et al. 4-Aryl-1,3,2-oxathiazolylium-5-olates as pH-controlled NO-donors: the next generation of S-nitrosothiols. J Am Chem Soc. 2007;129(17):5503-5514. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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CAY10563

Voir tous les produits spécifiques à Isoform NO Synthase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

CAY10563 Related Classifications

HY-181436 Related Classifications