Caylin-1
Caylin-1 is an inhibitor of MDM2 and an analog of Nutlin-3. Caylin-1 can bind to Bcl-XL and is used in multi-target anticancer research.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 1207480-88-3
- Formule: C30H28Cl4N4O4
- Masse moléculaire:650.38
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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CAS No. 1207480-88-3
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Masse moléculaire 650.38
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Formule C30H28Cl4N4O4
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SMILES
O=C1NCCN(C(N2[C@@H](C3=CC=C(Cl)C(Cl)=C3)[C@@H](C4=CC=C(Cl)C(Cl)=C4)N=C2C5=CC=C(OC)C=C5OC(C)C)=O)C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Shin J S, et al. Structural insights into the dual-targeting mechanism of Nutlin-3[J]. Biochemical and Biophysical Research Communications, 2012, 420(1): 48-53. [Content Brief]
[2]. Li J, et al. A cell-based high-throughput assay for the screening of small-molecule inhibitors of p53–MDM2 interaction[J]. Journal of biomolecular screening, 2011, 16(4): 450-456. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)