Chlorzolamide
Chlorzolamide (CL 13580) is a carbonic anhydrase (CA) inhibitor. Chlorzolamide has an effect on the skeletal muscle of rats, which can reduce the tetanic contraction force of soleus and extensor digitorum longus and prolong the relaxation time and peak time of muscle contraction. In addition, Chlorzolamide inhibits tumor cell proliferation and has antitumor activity.
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- CAS No.: 5541-92-4
- Formule: C8H6ClN3O2S2
- Masse moléculaire:275.74
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 5541-92-4
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Masse moléculaire 275.74
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Formule C8H6ClN3O2S2
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SMILES
O=S(N)(C1=NN=C(C2=C(Cl)C=CC=C2)S1)=O
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Synonyms
CL 13580
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Genis C, et al. Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties. Biochemistry. 2009 Feb 17;48(6):1322-31. [Content Brief]
[2]. Geers C, et al. Effects of carbonic anhydrase inhibitors on contraction, intracellular pH and energy-rich phosphates of rat skeletal muscle. J Physiol. 1990 Apr;423:279-97. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chlorzolamide Related Classifications
HY-171187 Related Classifications
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