CHMFL-KIT-031
CHMFL-KIT-031 is a highly selective KIT V559D inhibitor, with an IC50 of 28 nM. CHMFL-KIT-031 potently affects KIT V559D mutant’s phosphorylation at Y703/719/823 sites. CHMFL-KIT-031 inhibits the tumor growth in BaF3-TEL-KIT-V559D cell inoculated mouse model.
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- Formule: C26H25N5O5
- Masse moléculaire:487.51
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
IC50: 28 nM (KIT V559D); 168 nM (KIT wt)[1].
Chemical Information
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Masse moléculaire 487.51
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Formule C26H25N5O5
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SMILES
O=C(NCC(NC1=CC2=C(C=C1)C(/C=C/C3=NC=CC=C3)=NN2)=O)C4=CC(OC)=C(OC)C(OC)=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)