CL-242817
CL-242817 is an orally available angiotensin converting enzyme (ACE) inhibitor. CL-242817 inhibits the conversion of angiotensin I to angiotensin II and has blood pressure lowering activity. CL-242817 can also improve Monocrotaline (HY-N0750) induced lung injury. CL-242817 can be used in the study of pulmonary fibrosis and hypertension-related diseases.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 86709-48-0
- Formule: C18H21NO5S
- Masse moléculaire:363.43
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
CL-242817 effectively inhibits rabbit lung ACE in vitro (IC50=54.9 nM), angiotensin I (Al) induced contraction of isolated guinea pig ileum (IC50=0.82 pM), and enhances bradykinin (BK) induced contraction of isolated guinea pig ileum (EC50=0.383 pM)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 86709-48-0
-
Masse moléculaire 363.43
-
Formule C18H21NO5S
-
SMILES
O=C([C@H]1N(CCC1)C([C@H]([C@@H](C(C2=CC=CC=C2)=O)SC(C)=O)C)=O)O
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CL-242817 Related Classifications
HY-129213 Related Classifications
Powered by Bioz