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Cobolimab

(Synonyms: TSR-022; GSK4069889)
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Cobolimab (TSR-022) is an anti-TIM-3 monoclonal antibody. Cobolimab mediates the internalization of TIM3 with an IC50 value of 0.4464 nM. Cobolimab has potential application in solid tumors and non-small cell lung cancer (NSCLC).

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  • Pureté: 98.00%
  • CAS No.: 2022215-65-0
  • Masse moléculaire:142.84 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Cobolimab
  • Experimental Validation Results for Cobolimab
  • Experimental Validation Results for Cobolimab
  • Cobolimab Chemical Structure
    Cobolimab Chemical Structure
CAS No.: 2022215-65-0
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Cobolimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Flow cytometric analysis of 1.5X106 MCF-7 cells with Cobolimab (HY-P99827, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.

  • 1/16

    Loaded Cobolimab on AHC2 biosensor, can bind IL-1 beta Protein, Human (C-His, HY-P78459A) with an affinity constant of 7.523E-10 M as determined in BLI assay.

  • Cobolimab Chemical Structure
    1/16
  • Cobolimab
  • Flow cytometric analysis of 1.5X106 MCF-7 cells with Cobolimab (HY-P99827, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.
  • Loaded Cobolimab on AHC2 biosensor, can bind IL-1 beta Protein, Human (C-His, HY-P78459A) with an affinity constant of 7.523E-10 M as determined in BLI assay.