Copper tripeptide-3
Based on 1 Customer Validation
Copper tripeptide-3 (AHK-Cu) is a bioactive peptide with promotion of hair growth effect. Copper tripeptide-3 increases dermal cell proliferation and viability while increasing the deposition of collagen to renew the extracellular matrix. Copper tripeptide-3 stimulates the elongation of human hair follicles and proliferation of dermal papilla cells.
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- Pureté : 98.03%
- CAS No.: 767286-83-9
- Formule: C15H24CuN6O4
- Masse moléculaire:415.93
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Stockage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
Copper tripeptide-3 (10-100 μM, 3 d) increases the growth and viability of dermal fibroblasts while stimulating the production of collagen in normal human dermal fibroblasts[2].
Copper tripeptide-3 (10 pM-10 nM, 24 h) significantly stimulates the proliferation of cultured dermal papilla cells[1].
Copper tripeptide-3 (10 nM, 72 h) reduces the number of apoptotic dermal papilla cells by 3.48%[1].
Copper tripeptide-3 (10 nM, 24 h) increases Bcl-2 expression and decreases Bax expression in dermal papilla cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Normal human dermal fibroblasts
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Concentration:10-100 μM
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Incubation Time:3 d
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Result:Stimulated the formation of collagen type I by 300% compared to the control.
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Cell Line:Normal human dermal fibroblasts
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Concentration:10 nM
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Incubation Time:72 h
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Result:Downregulated the levels of cleaved capase-3 and PARP cleavage fragments by 42.7% and 77.5%.
Chemical Information
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CAS No. 767286-83-9
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Appearance Solid
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Masse moléculaire 415.93
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Formule C15H24CuN6O4
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Color Light blue to blue
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Synonyms
AHK-Cu
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Sequence
Ala-His-{Lys-Cu}
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Sequence Shortening
AH-{Lys-Cu}
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
In Vitro:
H2O : 25 mg/mL (60.11 mM; Need ultrasonic)
DMSO : 25 mg/mL (60.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 2.4043 mL | 12.0213 mL | 24.0425 mL | 60.1063 mL |
| 5 mM | 0.4809 mL | 2.4043 mL | 4.8085 mL | 12.0213 mL | |
| 10 mM | 0.2404 mL | 1.2021 mL | 2.4043 mL | 6.0106 mL | |
| 15 mM | 0.1603 mL | 0.8014 mL | 1.6028 mL | 4.0071 mL | |
| 20 mM | 0.1202 mL | 0.6011 mL | 1.2021 mL | 3.0053 mL | |
| 25 mM | 0.0962 mL | 0.4809 mL | 0.9617 mL | 2.4043 mL | |
| 30 mM | 0.0801 mL | 0.4007 mL | 0.8014 mL | 2.0035 mL | |
| 40 mM | 0.0601 mL | 0.3005 mL | 0.6011 mL | 1.5027 mL | |
| 50 mM | 0.0481 mL | 0.2404 mL | 0.4809 mL | 1.2021 mL | |
| 60 mM | 0.0401 mL | 0.2004 mL | 0.4007 mL | 1.0018 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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