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Cat. No.: HY-P11170

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D-Cateslytin

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D-Cateslytin is an antimicrobial peptide that exhibits potent inhibition activity against Candida albicans (MIC = 2.9 μM). D-Cateslytin can rapidly enter C. albicans, and shows no cytotoxicity to human gingival fibroblasts, and is stable in saliva. D-Cateslytin can be used for research on Candida albicans related diseases, such as oral candidosis.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Pureté: 99.44%
CAS No.: 3002053-77-9
Formule: C₈₁H₁₃₀N₃₀O₁₉S
Masse moléculaire:1860.15

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

D-Cateslytin Chemical Structure

CAS No.: 3002053-77-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Solvant et solubilité
- In Vitro
Pureté et documentation
Références
Help & FAQs
Classifications
Bioz

Activité biologique

Description

In Vitro

D-Cateslytin (0-100 μg/mL, 24-72 h) shows no cytotoxicity to human gingival fibroblasts (HFG-1) after 72 hours for concentrations up to 100 μg/mL ^[1].
D-Cateslytin (100-123 μM, 24 h) remains stable in the supernatant of Candida albicans, and remains stable in human saliva^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

HFG-1 cells
Concentration:

0-100 μg/mL
Incubation Time:

24, 48 and 72 h
Result:

Showed no cytotoxicity on HGF-1 after 72 hours for concentrations up to 100 μg/mL.

Chemical Information

CAS No. 3002053-77-9
Appearance Solid
Masse moléculaire 1860.15
Formule C₈₁H₁₃₀N₃₀O₁₉S
Color White to off-white
Sequence

d-{Arg-Ser-Met-Arg-Leu-Ser-Phe-Arg-Ala-Arg-Gly-Tyr-Gly-Phe-Arg}
Sequence Shortening

d{RSMRLSFRARGYGFR}
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvant et solubilité

In Vitro:

DMSO : 20 mg/mL (10.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

0.5376 mL

2.6880 mL

5.3759 mL

5 mM

0.1075 mL

0.5376 mL

1.0752 mL

10 mM

0.0538 mL

0.2688 mL

0.5376 mL

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Dartevelle P, et al. D-Cateslytin: a new antifungal agent for the treatment of oral Candida albicans associated infections. Sci Rep. 2018 Jun 18;8(1):9235. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	0.5376 mL	2.6880 mL	5.3759 mL	13.4398 mL
	5 mM	0.1075 mL	0.5376 mL	1.0752 mL	2.6880 mL
	10 mM	0.0538 mL	0.2688 mL	0.5376 mL	1.3440 mL

Keywords

MOQ

Minimum order quantity

100 mg

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Activité biologique
- Description
- In Vitro
Chemical Information
Solvant et solubilité
- In Vitro
Pureté et documentation
Références

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D-Cateslytin

Peptide Library

Activité biologique

Chemical Information

Solvant et solubilité

Pureté et documentation

Références

Help & FAQs

Complete Stock Solution Preparation Table

D-Cateslytin Related Classifications

HY-P11170 Related Classifications