country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-101779R

Copy Link Print Information

DCG04 (Standard)

DCG04 (Standard) is the analytical standard of DCG04 (HY-101779). This product is intended for research and analytical applications. DCG04 is a biotinylated activity-based probe. DCG04 labels calpain-1 and is applicable for affinity purification and mass spectrometry identification. DCG04 is used in cancer and malaria research.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 314263-42-8
Formule: C₄₃H₆₆N₈O₁₁S
Masse moléculaire:903.10

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DCG04 (Standard) Chemical Structure

CAS No.: 314263-42-8

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

HY-101779
DCG04

Cysteine Protease Inhibitor

Product Information
- Information
- Application
Chemical Information
Pureté et documentation
Calculators
Help & FAQs
Classifications
Bioz

Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 314263-42-8
Masse moléculaire 903.10
Formule C₄₃H₆₆N₈O₁₁S
SMILES

OC(C=C1)=CC=C1C[C@@H](C(NCCCCCC(N[C@H](C(N)=O)CCCCNC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O)=O)=O)NC([C@H](CC(C)C)NC([C@@H]4[C@H](O4)C(OCC)=O)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Références

[1]. Joyce JA, et al. Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis. Cancer cell. 2004 May;5(5):443-53.

[2]. Greenbaum D, et al. Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools. Chemistry & biology. 2000 Aug;7(8):569-81.

[3]. Yasothornsrikul S, et al. Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter. Proceedings of the National Academy of Sciences of the United States of America. 2003 Aug 05;100(16):9590-5.

[4]. Hillaert U, et al. Receptor-mediated targeting of cathepsins in professional antigen presenting cells. Angewandte Chemie (International ed. in English). 2009;48(9):1629-32. [Content Brief]

[5]. Song J, et al. Apoplastic effectors secreted by two unrelated eukaryotic plant pathogens target the tomato defense protease Rcr3. Proceedings of the National Academy of Sciences of the United States of America. 2009 Feb 03;106(5):1654-9.

[6]. Lee J, et al. Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumain. ACS chemical biology. 2010 Feb 19;5(2):233-43.

[7]. Arastu-Kapur S, et al. Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum. Nature chemical biology. 2008 Mar;4(3):203-13.

[8]. Chandramohanadas R, et al. Apicomplexan parasites co-opt host calpains to facilitate their escape from infected cells. Science (New York, N.Y.). 2009 May 08;324(5928):794-7.

[9]. Deu E, et al. Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo. Proceedings of the National Academy of Sciences of the United States of America. 2013 Nov 05;110(45):18244-9.

[10]. Shree T, et al. Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer. Genes & development. 2011 Dec 01;25(23):2465-79.

[11]. Sueldo DJ, et al. Activity-based proteomics uncovers suppressed hydrolases and a neo-functionalised antibacterial enzyme at the plant-pathogen interface. The New phytologist. 2024 Jan;241(1):394-408.

[12]. Rooney HC, et al. Cladosporium Avr2 inhibits tomato Rcr3 protease required for Cf-2-dependent disease resistance. Science (New York, N.Y.). 2005 Jun 17;308(5729):1783-6.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis