FAK-IN-24
FAK-IN-24 (Compound 9f) is a FAK inhibitor (IC50: 0.815 nM). FAK-IN-24 induces DNA damage and apoptosis. FAK-IN-24 has anti-glioblastoma activity. FAK-IN-24 inhibits proliferation of glioblastoma cell lines U87-MG (IC50 = 15 nM) and U251 (IC50 = 20 nM). FAK-IN-24 inhibits tumor growth in U87-MG xenograft model.
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- CAS No.: 3062175-62-3
- Formule: C39H45Cl2F3N8O3
- Masse moléculaire:801.73
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Chemical Information
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CAS No. 3062175-62-3
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Masse moléculaire 801.73
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Formule C39H45Cl2F3N8O3
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SMILES
O=C(CCCC1=CC=C(N(CCCl)CCCl)C=C1)OCCN2CCN(CC2)C3=CC=C(NC4=NC=C(C(F)(F)F)C(NC5=C(C(NC)=O)C=CC=C5)=N4)C=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)