CENATAC - centrosomal AT-AC splicing factor Gene

Also Known as MVA4; CCDC84; DLNB14

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 338657

About CENATAC

This gene has 10 transcripts (splice variants), 1 gene allele and 195 orthologues. Ubiquitous expression in skin (RPKM 3.1), spleen (RPKM 2.7) and 25 other tissues.

Summary

This gene encodes a protein thought to contain a coiled coil motif. No function has been determined for the encoded protein. A pseudogene of this gene is located on chromosome 20. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

CENATAC Products (1)

mRNA Protein Name
NM_198489.3 NP_940891.1 centrosomal AT-AC splicing factor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
Biological Process GO Annotation Evidence Références Source
involved in chromosome separation IMP
IMP: Inferred from mutant phenotype
34009673 GOA
involved in mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
34009673 GOA
involved in negative regulation of centrosome duplication IDA
IDA: Inferred from direct assay
31722219 GOA
involved in negative regulation of centrosome duplication IMP
IMP: Inferred from mutant phenotype
34009673 GOA
involved in regulation of protein catabolic process IMP
IMP: Inferred from mutant phenotype
31722219 GOA
Cellular Component GO Annotation Evidence Références Source
located in centrosome IDA
IDA: Inferred from direct assay
31722219 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CENATAC Protein Structure

CCDC84

CCDC84: Coiled coil protein 84 (7 - 325)

  • 0
  • 100
  • 200
  • 300
  • 332 a.a.
Protein Preferred Names Protein Names

centrosomal AT-AC splicing factor

  • coiled-coil domain containing 84

CENATAC Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
CENATAC Q86UT8 NDOR1 Homo sapiens Q9UHB4
Validated Y2H
32296183
Intra
CENATAC Q86UT8 ZNF114 Homo sapiens Q8NC26
Validated Y2H
32296183
Intra
CENATAC Q86UT8 TXNL4B Homo sapiens Q9NX01
Anti Tag CoIP
28514442
Intra
CENATAC Q86UT8 TXNL4B Homo sapiens Q9NX01
Validated Y2H
32296183
Intra
CENATAC Q86UT8 TXNL4B Homo sapiens Q9NX01
Anti Tag CoIP
33961781
Intra
CENATAC Q86UT8 MESD Homo sapiens Q14696
Y2H Array
32296183
Intra
CENATAC Q86UT8 MESD Homo sapiens Q14696
Y2H Prey Pooling
32296183
Intra
CENATAC Q86UT8 MRPL38 Homo sapiens Q96DV4
Validated Y2H
32296183
Intra
CENATAC Q86UT8 MRPL38 Homo sapiens Q96DV4
Y2H Array
32296183
Intra
CENATAC Q86UT8 MRPL38 Homo sapiens Q96DV4
Y2H Prey Pooling
32296183
Intra
CENATAC Q86UT8 PPIL3 Homo sapiens Q9H2H8
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Intellectual Developmental Disorder, Autosomal Dominant 5

  • MRD5

  • Autosomal Dominant Non-Syndromic Intellectual Disability 5

  • Intellectual Disability, Autosomal Dominant 5

  • Mental Retardation, Autosomal Dominant 5

  • Autosomal Dominant Intellectual Developmental Disorder 5

  • Syngap1-Related Non-Syndromic Intellectual Disability

  • Autosomal Dominant Intellectual Disability 5

  • Syngap1 Syndrome

  • Syngap1-Related Nsid

  • Syngap1 Gene Mutation Linked To Intellectual Disability, Schizophrenia And Autism
Microcephalic Osteodysplastic Primordial Dwarfism, Type I

  • Taybi-Linder Syndrome

  • Brachymelic Primordial Dwarfism

  • Cephaloskeletal Dysplasia

  • Low-Birth-Weight Dwarfism With Skeletal Dysplasia

  • Microcephalic Osteodysplastic Primordial Dwarfism Type I

  • Osteodysplastic Primordial Dwarfism Type I

  • Primordial Microcephalic Dwarfism, Crachami Type

  • Osteodysplastic Primordial Dwarfism, Type 1

  • MOPD1

  • Mopd I

  • Mopd

  • Osteodysplastic Primordial Dwarfism, Type I

  • Tals

  • Microcephalic Osteodysplastic Primordial Dwarfism Type 1

  • Mopd 1

  • Microcephalic Osteodysplastic Primordial Dwarfism Types 1 And 3

  • Microcephalic Osteodysplastic Primordial Dwarfism Types I And Iii

  • Mopd Types I And Iii

  • Microcephalic Osteodysplastic Primordial Dwarfism, Taybi-Linder Type

  • Primordial Microcephalic Dwarfism Crachami Type

  • Dwarfism, Primordial, Osteodysplastic, Microcephalic, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS02471 CENATAC Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CENATAC VGNC VGNC:38862
Felis catus CENATAC VGNC VGNC:60520
Mus musculus CENATAC MGD MGI:2685960
Macaca mulatta CENATAC VGNC VGNC:100909
Bos taurus CENATAC VGNC VGNC:26922
Rattus norvegicus CENATAC RGD RGD:1597440
Others CENATAC NCBI