hAChE-IN-9
hAChE-IN-9 (compound 7i) is a selective inhibitor of human acetylcholinesterase (hAChE) with IC50 of 0.05 μM and 2.85 μM for AChE and BChE, respectively. hAChE-IN-9 modulates toxic Aβ oligomer forms into non-toxic ones and has antioxidant and neuroprotective effects against Aβ-induced toxicity. hAChE-IN-9 can be used for the study of Alzheimer's disease.
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- Formule: C20H15ClN6O4S
- Masse moléculaire:470.89
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
[1]|
hAChE 0.05 μM (IC50) |
hBCHE 2.85 μM (IC50) |
Chemical Information
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Masse moléculaire 470.89
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Formule C20H15ClN6O4S
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SMILES
O=C(/C(C#N)=C(SC)/NC1=CC=C([N+]([O-])=O)C=C1)NN2C(CCl)=NC3=CC=CC=C3C2=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)