hCAIX-IN-5
Based on 1 Customer Validation
hCAIX-IN-5 (compound 6b) is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively.
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- Pureté: 98.32%
- CAS No.: 2451479-57-3
- Formule: C18H12FNO3
- Masse moléculaire:309.29
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Stockage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Activité biologique
KI: >10000 nM (hCAI); >10000 nM (hCAII); 130.7 nM (hCAIV); 829.1 nM (hCAIX)[1]
Chemical Information
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CAS No. 2451479-57-3
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Appearance Solid
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Masse moléculaire 309.29
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Formule C18H12FNO3
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Color Off-white to light brown
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SMILES
O=C(NC1=CC2=C(OC(C=C2)=O)C=C1)/C=C/C3=CC=C(C=C3)F
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvant et solubilité
DMSO : 50 mg/mL (161.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2332 mL | 16.1661 mL | 32.3321 mL | 80.8303 mL |
| 5 mM | 0.6466 mL | 3.2332 mL | 6.4664 mL | 16.1661 mL | |
| 10 mM | 0.3233 mL | 1.6166 mL | 3.2332 mL | 8.0830 mL | |
| 15 mM | 0.2155 mL | 1.0777 mL | 2.1555 mL | 5.3887 mL | |
| 20 mM | 0.1617 mL | 0.8083 mL | 1.6166 mL | 4.0415 mL | |
| 25 mM | 0.1293 mL | 0.6466 mL | 1.2933 mL | 3.2332 mL | |
| 30 mM | 0.1078 mL | 0.5389 mL | 1.0777 mL | 2.6943 mL | |
| 40 mM | 0.0808 mL | 0.4042 mL | 0.8083 mL | 2.0208 mL | |
| 50 mM | 0.0647 mL | 0.3233 mL | 0.6466 mL | 1.6166 mL | |
| 60 mM | 0.0539 mL | 0.2694 mL | 0.5389 mL | 1.3472 mL | |
| 80 mM | 0.0404 mL | 0.2021 mL | 0.4042 mL | 1.0104 mL | |
| 100 mM | 0.0323 mL | 0.1617 mL | 0.3233 mL | 0.8083 mL |