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Cat. No.: HY-176058

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HDAC6-IN-57

HDAC6-IN-57 (compound 9c) is an HDAC6 inhibitor with an IC₅₀ value of 7 nM. HDAC6-IN-57 inhibits 60 cancer cell lines with a mean GI₅₀ of 2.64 μM while exhibiting significantly lower cytotoxicity towards non-tumor cell lines.

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Formule: C₂₇H₂₉BrN₄O₄
Masse moléculaire:553.45

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

HDAC6-IN-57 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

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Chemical Information

Masse moléculaire 553.45
Formule C₂₇H₂₉BrN₄O₄
SMILES

O=C(NO)CCCCCCN1CC(N2[C@H](C1=O)CC3=C([C@@H]2C4=CC=CC(Br)=C4)NC5=CC=CC=C53)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Aya Fathy, et al. Development of potent and selective tetrahydro-β-carboline-based HDAC6 inhibitors with promising activity against triple-negative breast cancer. RSC Med Chem. 2025 Apr 17. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
Pureté et documentation
Références

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HDAC6-IN-57

Voir tous les produits spécifiques à Isoform HDAC

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

HDAC6-IN-57 Related Classifications

HY-176058 Related Classifications

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